Description
In 1927, Cecil A. Alport make research on this disease. He stated that alport syndrome is a disease where the kidneys derived disrupted. Alport syndrome derived from kidney inflammation. Women can transmit the gene for this disease, to their children if they have no symptoms.
Occurred COL4A3 and COL4A5 gene mutations in this disease. The gene provides instructions for creating one of the protein components of collagen type IV. These proteins play an important role in the kidney, especially in the structures called glomeruli. Glomerulli is a special group of blood vessels that berfunsi remove water and waste products daari blood and make urine.
Factors that influence risk include: nephritis, hearing loss before the age of 30, syndromes alport in family history.
Phenomenon
The disease is characterized by kidney disease, hearing loss, and kelaianan eye.
Treatment
Treatment for this disease is by gene therapy.
In 1927, Cecil A. Alport make research on this disease. He stated that alport syndrome is a disease where the kidneys derived disrupted. Alport syndrome derived from kidney inflammation. Women can transmit the gene for this disease, to their children if they have no symptoms.
Occurred COL4A3 and COL4A5 gene mutations in this disease. The gene provides instructions for creating one of the protein components of collagen type IV. These proteins play an important role in the kidney, especially in the structures called glomeruli. Glomerulli is a special group of blood vessels that berfunsi remove water and waste products daari blood and make urine.
Factors that influence risk include: nephritis, hearing loss before the age of 30, syndromes alport in family history.
Phenomenon
The disease is characterized by kidney disease, hearing loss, and kelaianan eye.
Treatment
Treatment for this disease is by gene therapy.
